A woman tranformed into a giant after she is struck by a meteorite on her wedding day becomes part of a team of monter sent in by the U.S. government to defeat an alien mastermind trying to take over Earth.
      When a meteorite from outer space hits a young California woman named Susan Murphy and turn her into a giant monter, she is taken to a secret government compound where she meets a ragtag group of monter also rounded up over the year. As a last resort, under the guidance of General W.R. Monger, on a desperate order from The President, the motley crew of Monter is called into action to combat the alien and save the world from imminent destruction!

Susan (Reese Witherspoon voice) play a small living in California, she was born here, go to school here, is here to love, it was her Mr. Right to enter the wedding hall wedding day, if there is no accident, her life also to this stereotyping ---- However, when the priest called her if she would marry in front of her fiance the unthinkable happened: her body even rapid growth of several times the volume, even bursting of the church of the wedding! Soaring Susan overwhelmed by the facing side of all, her husband, her family, she lived in the house, everything is becoming smaller and smaller ... When Susan woke up again she found herself In an institute. Institute investigator told her that strange things happened to her is not by chance, in fact, because of her contact with extraterrestrial objects, contact with visitors from outer space any object, it is possible any changes in his body, while the In contrast, the changes in Susan's is fairly easy one. Within the Institute, Susan has found a variety of creatures like her have the same trouble, and some turned into a cockroach-like insects (voice of Hugh Laurie), and some become strange with nose gelatinous viscous Bob (voice of Seth Rogan), some into a half-ape, half-fish Link (Will A Naite dubbing), and larvae an enormous ...... these extraterrestrial biological contamination people are gathered together in their possession all night to study, hoping to find a solution. But Susan, how can they like to be portrait look how surprising things like research to study go? They shout the Institute in a vain attempt to escape this place, but in the end they are all without success. Say, Susan, a pedestrian who's wrong not to get rid of the alien has already done the attack preparations. Alien technology is too developed, and the armies of the aliens is a huge metal robot in front of these steel monsters, the earth soon rival army, seeing the civilization of the earth would be destroyed, senior government finally had a dead horse as living horse medicine, to help these monsters within the Institute. Because of the various characteristics of them, fear of physical weapons to combat, so they might be able to defeat the aliens instead. Susan, although they reluctant to be used by the government acting as a proxy, but it comes to such a major mission to defend the Earth, they inverted the cardinal principles. So these different patterns of monster himself various characteristics of the beginning of the war came from extraterrestrial shaped ...