Cheng Jun was to see his parents paid doctors engaged in occupation of hard, but love medicine Cheng Junyi however chose to become an emergency physicians. The doctor working pressures, but Lotte Cheng Jun still can find happiness. When brought his own grandmother suddenly was diagnosed with advanced liver cancer, Cheng Jun pain unceasingly, as a doctor but save grandma's life. Cheng Jun love with Department of doctor Ouyang Yulu, returned from the USA big brother Shen Qingchuan to join the heart surgery of Xihua hospital, also launched a strong attack on Ouyang. The addition of Shen Qingchuan, so that Ouyang, Cheng Jun into the whirlpool of feelings. The new assigned to the emergency department 3 interns to the emergency room has brought a lot of trouble, but also add a lot of stories to the collective. Cheng Jun and the emergency room of the small collective, overcome difficulties, in the treatment of patients in the process of continuous mining exercise self, medical ethics, adhere to explore and guard in the career path, find the emergency room to safeguard the meaning of life.