A woman and her teenage daughter become imprisoned in the panic room of their own house by 3 criminals.
Recently divorced Meg Altman and her daughter Sarah have bought a new home in New York. On their tour around the manion, they come across the panic room. A room so secure, that no one can get in. When three burglar break in, Meg makes a move to the panic room. But all her troubles don't stop there. The criminals know where she is, and what they require the most in the house is in that very room.

Meg ( Jodie Foster ornaments ) is a single mother with her only daughter , in order to get rid of the shadow of a failed marriage , she moved into an exclusive residential area of New York , is almost always an emergency shelter in the buildings of New York room, Meg 's new home also has one of the numerous organs of the chamber of Secrets , which is designed to cope with the burglary, robber , adequate water , food and other necessities in the room is also equipped with a set of closed-circuit monitoring system , just like a improve the emergency shelter . Meg moved into the first night , bad luck , the three robbers broke into her home , unruffled Meg emergency hid with her daughter to the secret room . But the goal of the three thugs is not Meg property , but a cash hidden in the secret room concealed , hid in the secret room of the mother and daughter so suddenly thrown into a more dangerous situation . To protect themselves, Meg use wit the game of "cat and mouse " and criminals in this small space , the dilemma under a deal of life and death begins